Shiatsu is recognized for its beneficial effects on a wide spectrum of functional disorders. Stress and anxiety, musculoskeletal pain, digestive issues, insomnia, headaches, chronic fatigue, menstrual disorders: finger pressure along meridians stimulates the body's natural self-regulation mechanisms. Recent clinical studies confirm its value for stress, pain and cancer-related fatigue management. This article presents main indications, contraindications and current scientific research.